This study aimed to create a hand sanitizer using natural materials, emphasizing the importance of hand hygiene in preventing the spread of infections. The results indicated that all the prepared hand sanitizers met the acceptable criteria for organoleptic characteristics. The pH of the formulations ranged from 5 to 6. A study involving 20 human volunteers evaluated the acceptability of the hand sanitizer. It was found that the hand sanitizer had a pleasant smell, providing a positive sensory experience during usage. Among the volunteers, 75% expressed a preference for F3 over F1 and F2. Based on these findings, it can be concluded that F3 was the preferred choice for the majority of the volunteers, suggesting its superiority among all the formulations.