has long been prized in traditional medicinal systems for its numerous therapeutic applications. The pharmacological potential of the plant’s roots, stem, flower, and leaves—including their antibacterial, hepatoprotective, anticancer, antifertility, antiulcer, antifungal, and wound-healing properties—has been evaluated in a number of research. The goal of this paper is to provide a succinct overview of the ethnobotanical applications, phytochemistry, putative pharmaceutical actions, facts, and phytoconstituents of this precious plant. A thorough review of the literature was conducted using a variety of online resources, including PubMed, Science Direct, Springer, and Google Scholar. All of the papers were based on pharmacological characteristics and traditional therapeutic applications. According to the detailed findings, P. auriculata has great potential for treating serious illnesses like diabetes, heart disease, ulcers, liver issues, obesity, wound healing, cancer, and more. This analysis also highlights current limitations, including toxicity concerns, a lack of comprehensive clinical trials, and the need for standardized phytochemical profiling.

Keywords: Plumbago auriculata, Cape leadwort, Pharmacology, Tradition, Antioxidant, Anti-inflammatory, Antimicrobial, Anticancer, Neuroprotective