Rapid Onset of Action of Mirtazapine : A Review illustrating its benefits and risks over SSRI
Author: Md. Wasioullah, Surbhi Tyagi, Ammu Muraleedharan, Urvashi Dhawal, Dr. Rajveer Singh
Abstract:
Depressive disorders have become a serious illness affecting millions worldwide, which prominently
affects day to day life activities of patients affected with the disorder. It becomes a long term illness
gradually requiring prompt therapy to prevent certain risk associated with the illness chiefly suicidal
risk. Traditional antidepressants generally required weeks to months to generate any response from
patients, having delayed onset of action which may become cumbersome and quite expensive for the
population in need. However, the introduction of certain antidepressants with a faster onset of action,
such as mirtazapine changed the conventional approaches. Electronic search was performed to identify
and include relevant studies done under topic of interest since from 1999 to 2020. This paperbriefly
reviews the various published literature on mirtazapine to come up with sufficient evidence illustrating
its faster onset of action compared to several other antidepressants using certain comparison studies
emphasizing its benefits along with risk.
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